[55216-31-4] · C33H66ClFe3O16 · m3-Oxohexakis(m-trimethylacetato)tris(methanol)triiron(III) Chloride · (MW 921.99)
(one of several (m3-oxo)triiron cluster complexes used to catalyze the epoxidation of alkenes with molecular oxygen1)
Physical Data: orange-yellow crystalline solid.
Preparative Methods: equimolar aqueous solutions of FeIIICl3 and sodium pivalate are mixed and the resulting precipitate is filtered and dried in vacuo.2
Purification: recrystallization from chloroform-methanol.
[Fe3O(OPiv)6(MeOH)3]+Cl- (Piv = OCCMe3) is a useful catalyst for the epoxidation of alkenic alcohol acetates with molecular oxygen. The reaction requires one equivalent of oxygen to effect the peroxidation, half of which is apparently consumed in undesirable side reactions. The regiospecificity of the oxidation is similar to that observed when conventional peroxy acid epoxidation reagents are used,4 but is opposite to that observed under Sharpless epoxidation conditions.5 This polynuclear transition metal catalyst affords higher yields and better selectivity than alternative transition metal catalysts known to effect alkene epoxidation with oxygen. However, two particularly good alternatives are [Fe3O(OAc)6(H2O)3](OAc)
Mark W. Zettler
The Dow Chemical Company, Midland, MI, USA