[7783-35-9] · HgO4S · Mercury(II) Sulfate · (MW 296.66)
Alternate Name: mercuric sulfate.
Physical Data: mp dec; d 6.470 or 7.56 g cm-3.
Solubility: insol H2O (dec into a yellow, basic sulfate); sol HCl, hot dil H2SO4, HNO3, and conc solution of NaCl.
Form Supplied in: white, odorless, monoclinic crystals, granules, or powder.
Handling, Storage, and Precautions: acute poison; exposure to all mercury compounds is to be strictly avoided. Releases toxic Hg fumes when heated to decomposition. Protect from light.
In combination with strong acids1-4 or Dowex 50,4,5 HgSO4 is often employed as a catalyst for effecting hydration of alkynes, which results in the formation of the corresponding ketones (eq 1). This strategy has been used in the synthesis of 19-norprogesterone6 and histamine.3b
D-Glucal has been found to produce (2R)-(1,2-dihydroxyethyl)furan when treated with HgSO4/H2SO4 (eq 2).7 Other glycals undergo hydration or elimination.8
Similarly to other mercury(II) salts, HgSO4 effects hydrolysis of vinyl halides to ketones9 and allylic oxidation (Deigès reaction).10
University of Leicester, UK