Lithium Aluminum Hydride-Diphosphorus Tetraiodide

LiAlH4-P2I4
(LiAlH4)

[16853-85-3]  · AlH4Li  · Lithium Aluminum Hydride-Diphosphorus Tetraiodide  · (MW 37.96) (P2I4)

[13455-00-0]  · I4P2  · Lithium Aluminum Hydride-Diphosphorus Tetraiodide  · (MW 569.54)

(reducing system for converting aromatic ketones to hydrocarbons)

Physical Data: see Lithium Aluminum Hydride. Diphosphorus tetraiodide: mp 125-128 °C.

Form Supplied in: see Lithium Aluminum Hydride. Diphosphorus tetraiodide: orange needles (recrystallized from methylene chloride); available commercially or can be prepared from PCl3 and KI.1

Analysis of Reagent Purity: see Lithium Aluminum Hydride.

Handling, Storage, and Precautions: see Lithium Aluminum Hydride. Diphosphorus tetraiodide: should be protected from light, and stored under nitrogen.

Reductions of Aromatic Ketones to Hydrocarbons.

This combination of reagents (1:1 ratio) reduces aromatic ketones to hydrocarbons in refluxing benzene solvent (eqs 1-3).2 The process may be used to introduce deuterium via use of LiAlD4 (eq 4).3


1. Newkome, G. R.; Sauer, J. D.; Erbland, M. L. CC 1975, 885.
2. Suzuki, H.; Masuda, R.; Kubota, H.; Osuka, A. CL 1983, 909.
3. Radtke, R.; Heesing, A. CB 1990, 123, 621.

MaryGail K. Hutchins

King of Prussia, PA, USA

Robert O. Hutchins

Drexel University, Philadelphia, PA, USA



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