[2565-30-2] · CHClO · Formyl Chloride · (MW 64.47)
Physical Data: unstable at room temperature.
The procedure described by Gatterman and Koch1 for the preparation of p-tolualdehyde calls for stirring a suspension of Copper(I) Chloride and Aluminum Chloride in toluene and passing in Carbon Monoxide and Hydrochloric Acid and hydrolyzing the resulting complex with ice. Formyl chloride was regarded as the transient intermediate (eq 1).
Treatment of 4-(1-hydroxyethyl)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene and its position isomers with Formic Acid and Thionyl Chloride gave in 65% yield the three double bond isomers of 4-(1-formyloxyethyl)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene (eq 2).2
John C. Sih
The Upjohn Co., Kalamazoo, MI, USA